We published an original hypothesis in Life Extension Magazine teaching that the macula  is affected by low hormones.  

Download Neurosteroids and the Retina to better appreciate the role of hormones in the macula.  Another interesting article that I recommend is the Holtorf article. 

Remember these points: 

1. The macula does have the UNIQUE biochemistry to make hormone

2.  Blood levels of hormone are very low in macular patients as compared to age matched controls without the disease. 

3.  Cholesterol, the building block of hormones exist in drusen. 

4.  Lower hormone levels in macular degeneration patients can account for the increased risk cardiovascular disease known to be associated with macular degeneration.

5.  NEW:  Low hormones result in abnormal stem cell physiology.  It is intriguing to think that stem cell dysfunction may be another modulator of macular degeneration.  

We believe that the macula of a patient with macular degeneration is trying to make hormones but it cannot.  The BIG question is whether restoring blood levels of hormones will protect the macula.   We hope/think so since recent studies are suggesting the current model of "vitamins" is not working to prevent this disease.  At the very least restoring physiology (www.dzugan.com) will profoundly improve the quality of life of patients.